Two photos combined: Democratic U.S. Senate candidate Scott Colom raising his fist at a campaign rally in Jackson, Miss., on Oct. 14, 2026, and Mississippi Sen. Cindy Hyde-Smith walking to the stage in Corinth, Miss.

Investors have poured more than $35M into prediction markets for the uncalled United States Senate race in Mississippi. The tight contest pits Republican incumbent Cindy Hyde-Smith against Democrat Scott Colom.