US estrogen shortages widen to injections and creams

US estrogen shortages are widening beyond patches to include injections and vaginal creams as demand surges for hormone replacement therapy following the removal of a federal boxed warning.

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FILE PHOTO: US President Donald Trump presents an executive order on women's health, spearheaded by first lady Melania Trump, with his and the first lady's signatures, in the Rose Garden at the White House in Washington, DC, US, October 19, 2026.  REUTERS/Umit Bektas/File Photo

Women across the United States face a widening shortage of hormone replacement therapies as surging demand spills over from scarce patches into injectable and vaginal treatments. The shortages follow the removal of a long-standing boxed cancer warning on hormone therapy. Patients are increasingly seeking alternative treatments to manage menopause symptoms.